Asymmetric transformations involving 1,2-diarbonyl compounds as pronucleophiles - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Chemical Communications Année : 2012

Asymmetric transformations involving 1,2-diarbonyl compounds as pronucleophiles

Wilfried Raimondi
  • Fonction : Auteur
Damien Bonne
Connectez-vous pour contacter l'auteur
Jean Rodriguez
  • Fonction : Auteur
  • PersonId : 921781

Résumé

This article concentrates on the versatile nucleophilic reactivity of 1,2-dicarbonyl compounds in various asymmetric transformations. Although underexploited in comparison to their 1,3-dicarbonyl homologues, the presence of adjacent multiple reactive centres allows the selection of specific activation modes for enhancing the reactivity of these important ambident pronucleophiles. They can be involved in selective formation of C-C, C-O or C-N bonds leading to various optically active targets in the acyclic and cyclic series including three- to seven-membered ring systems. Recent contributions in the field of biochemical, organometallic and organic catalytic transformations as well as some relevant stoichiometric approaches are discussed from synthetic and mechanistic point of views highlighting some important stereochemical issues.

Mots clés

Domaines

Chimie organique
Fichier principal
Vignette du fichier
HAL25.pdf (1.17 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-00736692 , version 1 (28-09-2013)

Identifiants

Citer

Wilfried Raimondi, Damien Bonne, Jean Rodriguez. Asymmetric transformations involving 1,2-diarbonyl compounds as pronucleophiles. Chemical Communications, 2012, 48, pp.6763-6775. ⟨10.1039/C2CC30691C⟩. ⟨hal-00736692⟩
134 Consultations
605 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More