A novel device for continuous flow magnetic trapping and sorting of human cells using flat micro-patterned NdFeB films

Osman Osman (1) , Cyrille Vézy (1) , Jérémy Pivetal (1) , Marie Frénéa-Robin (1) , Naoufel Haddour (1) , François Buret (1) , Luiz-Fernando Zanini (2) , Gilbert Reyne (3) , Nora Dempsey (2) , Frédéric Dumas-Bouchiat (2)

1 AMPERE - Ampère
2 NEEL - MNM - Micro et NanoMagnétisme
3 G2ELab - Laboratoire de Génie Electrique de Grenoble

The manipulation of magnetically labeled bio-objects of nano or micrometer sizes is now realizable by combining the magnetic forces with microfluidics. This paper reports a novel method for manipulating, trapping and sorting magnetic beads and magnetically labeled cells under continuous flow. This method uses a microfluidic device with integrated flat micro-patterned hard magnetic films which generate high magnetic field gradients.

Mots clés: Magnetism; Cell separation; Microfluidic

Domaines: Energie électrique

Osman Osman, Cyrille Vézy, Jérémy Pivetal, Marie Frénéa-Robin, Naoufel Haddour, et al.. A novel device for continuous flow magnetic trapping and sorting of human cells using flat micro-patterned NdFeB films. MicroTAS, Oct 2010, Groningen, Netherlands. pp.515-517. ⟨hal-00734020⟩