Study on the migration of bisphenol a from polycarbonate baby bottles purchased in the Spanish market by liquid chromatography and fluorescence detection
Résumé
During the last decade the safety in the use of BPA monomer in polycarbonate baby bottles, has drawn the attention from the public and the scientific community. This paper presents the results of Bisphenol A migration from polycarbonate baby-bottles bought in the Spanish market, into simulants B and E (3% acetic acid and 50% ethanol, respectively) and into real food (reconstituted infant formula). Furthermore, it was also the objective of this study to assess the suitability of 50% ethanol as simulant for infant formula. BPA was analyzed by a multianalyte liquid chromatography method with fluorescence detection and mass spectrometry confirmation. The method was in-house validated and accredited by the national accreditation body. The validation results for this analyte in the previous mentioned matrices were: LOD: 0.004-0.007 mg.kg-1; LOQ (validated): 0.03 mg.kg-1; RSD%: 3.4-5.8; recovery: 106.6-118.2%. A collection of 72 different baby-bottle samples from 12 different brands were analyzed. Baby-bottle material was identified by FTIR. The migration test conditions used were those recommended for baby bottles in the Guidelines on testing conditions for articles in contact with foodstuffs (with a focus on kitchenware), prepared by the European network of laboratories for food contact materials. In most of the migration assays the results were under the detection limit. In four of the commercial brands there was detectable migration into the simulant 50% ethanol and only in two samples BPA was detected in infant formula (0.01 mg.kg-1). Migration results obtained were in compliance with the European Union regulation.
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