Accuracy of sentinel lymph node biopsy after neo-adjuvant chemotherapy in patients with locally advanced breast cancer and clinically positive axillary nodes

Giuseppe Canavese (1) , Beatrice Dozin (2) , Carlo Vecchio (1) , Daniela Tomei (1) , Giuseppe Villa (3) , Franca Carli (2) , Lucia del Mastro (2) , Alessia Levaggi (2) , Carlo Rossello (2) , Stefano Spinaci (2) , Paolo Bruzzi (2) , Alessandra Catturich (1)

1 National Cancer Research Institute Genova
2 National Cancer Research Institute
3 Department of Nuclear Medicine

Feasibility and accuracy of sentinel node biopsy (SLNB) after the delivery of neo-adjuvant chemotherapy (NAC) is controversial. We here report our experience in NAC-treated patients with locally advanced breast cancer and clinically positive axillary nodes, and compare it with the results from our previous randomized trial assessing SLNB in early-stage breast cancer patients.

Mots clés: :axillary lymph node dissection; locally advanced breast cancer; lymphatic mapping; neo-adjuvant chemotherapy; sentinel node biopsy

Giuseppe Canavese, Beatrice Dozin, Carlo Vecchio, Daniela Tomei, Giuseppe Villa, et al.. Accuracy of sentinel lymph node biopsy after neo-adjuvant chemotherapy in patients with locally advanced breast cancer and clinically positive axillary nodes. EJSO - European Journal of Surgical Oncology, 2011, 37 (8), pp.688. ⟨10.1016/j.ejso.2011.05.012⟩. ⟨hal-00715501⟩