Type IV Collagen as a Tumour Marker for Colorectal Liver Metastases

H. Nyström (1) , P. Naredi (1) , L. Hafström (1) , M. Sund (1)

1 Department of Surgical and Perioperative Sciences/ Surgery

About 50% of patients with primary colorectal cancer (CRC) will develop liver metastases (CLM). Currently, carcinoembryonic antigen (CEA) is the most common tumour marker for CRC and CLM. However, the sensitivity and specificity of this marker is not optimal, as almost 50% of patients have tumours that do not produce CEA. Therefore there is a need for better markers for CRC and CLM.

Mots clés: Collagen; Basement membrane; Stroma; Biomarker; Cancer

H. Nyström, P. Naredi, L. Hafström, M. Sund. Type IV Collagen as a Tumour Marker for Colorectal Liver Metastases. EJSO - European Journal of Surgical Oncology, 2011, ⟨10.1016/j.ejso.2011.04.010⟩. ⟨hal-00710919⟩