Biomarkers in asthma and allergic rhinitis

Z. Diamant (1) , J.D. Boot , E. Mantzouranis (2) , R. Flohr , P.J. Sterk (3) , R. Gerth van Wijk (4)

1 Depts of Allergology and Pulmonology
2 Division of Allergy
3 AcademicMedical Center
4 Son Pisa Primary Care Centre

A biological marker (biomarker) is a physical sign or laboratory measurement that can serve as an indicator of biological or pathophysiological processes or as a response to a therapeutic intervention. An applicable biomarker possesses the characteristics of clinical relevance (sensitivity and specificity for the disease) and is responsive to treatment effects, in combination with simplicity, reliability and repeatability of the sampling technique. Presently, there are several biomarkers for asthma and allergic rhinitis that can be obtained by non-invasive or semi-invasive airway sampling methods meeting at least some of these criteria.

Mots clés: Medicine

Domaines: Pneumologie et système respiratoire

Z. Diamant, J.D. Boot, E. Mantzouranis, R. Flohr, P.J. Sterk, et al.. Biomarkers in asthma and allergic rhinitis. Pulmonary Pharmacology & Therapeutics, 2010, 23 (6), pp.468. ⟨10.1016/j.pupt.2010.06.006⟩. ⟨hal-00699040⟩