Sentinel Lymph Node Biopsy in Early Breast Cancer Surgery - working with the risks of vital blue dye to reap the benefits

V. White (1) , J.R. Harvey (1) , C.D.M. Griffith (1) , M. Youssef (1) , M. Carr (1)

1 Department of Breast Surgery

Sentinel lymph node biopsy (SLNB) is an important method of staging early breast cancer because of the inherent benefits it confers on patients in terms of arm function and quality of life. Its success depends on a high level of accuracy in detecting the sentinel node. This is achieved by a dual mapping technique that employs a radio-labelled nanocolloid and a vital blue dye. The vital dyes however carry the risk of anaphylaxis, and as more surgeons employ SLNB in their daily practice, a proportionate rise in the number of anaphylactic reactions can be expected. A comprehensive review of risks and benefits associated with using vital blues dyes has not been published and therefore a retrospective review was undertaken of the different levels of anaphylaxis associated with vital dyes, their benefit to SLNB and methods of reducing the risk.

Mots clés: Medicine

V. White, J.R. Harvey, C.D.M. Griffith, M. Youssef, M. Carr. Sentinel Lymph Node Biopsy in Early Breast Cancer Surgery - working with the risks of vital blue dye to reap the benefits. EJSO - European Journal of Surgical Oncology, 2011, 37 (2), pp.101. ⟨10.1016/j.ejso.2010.12.007⟩. ⟨hal-00663073⟩