Ubiquitin ligase switch in plant photomorphogenesis: A hypothesis

Alexandra Pokhilko (1) , Jason A. Ramos , Hans Holtan , Don R. Maszle , Rajnish Khanna , Andrew J. Millar (1, 2)

1 Edin. - University of Edinburgh
2 Centre for Systems Biology at Edinburgh

The E3 ubiquitin ligase COP1 (CONSTITUTIVE PHOTOMORPHOGENIC1) plays a key role in the repression of the plant photomorphogenic development in darkness. In the presence of light, COP1 is inactivated by a mechanism which is not completely understood. This leads to accumulation of COP1's target transcription factors, which initiates photomorphogenesis, resulting in dramatic changes of the seedling's physiology.

Mots clés: Arabidopsis thaliana; Mathematical model; Systems biology; HY5/ HFR1

Alexandra Pokhilko, Jason A. Ramos, Hans Holtan, Don R. Maszle, Rajnish Khanna, et al.. Ubiquitin ligase switch in plant photomorphogenesis: A hypothesis. Journal of Theoretical Biology, 2011, 270 (1), pp.31. ⟨10.1016/j.jtbi.2010.11.021⟩. ⟨hal-00656343⟩