 |
|
|
|
| HAL : hal-00643521, version 1 |
| Fiche détaillée |  Récupérer au format |
|
|
| US 2011/0245478 (06/10/2011) - |
|
|
|
|
| Method for the synthesis of oligonucleotide derivatives |
|
|
| Morvan François 1Meyer Albert 1 |
|
|
| (06/10/2011) |
|
|
|
| Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted to the oligonucleotide with the help of a "click chemistry" reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting |
|
|
|
|
|
|
|
|
|
|
|
| 1 : | Institut des Biomolécules Max Mousseron (IBMM) |
|
|
|
CNRS : UMR5247 – Université Montpellier I – Université Montpellier II - Sciences et techniques |
|
|
| 2 : | Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS) |
|
|
|
CNRS : UMR5246 – Université Claude Bernard - Lyon I – Institut National des Sciences Appliquées (INSA) - Lyon – École Supérieure Chimie Physique Électronique de Lyon |
|
|
| 3 : | Institut des nanotechnologies de Lyon - Site d'Ecully (INL) |
|
|
|
CNRS : UMR5270 – Université Claude Bernard - Lyon I – Institut National des Sciences Appliquées (INSA) - Lyon – Ecole Centrale de Lyon |
|
|
|
|
|
|
|
|
|
| Domaine | : | Chimie/Chimie organique |
| hal-00643521, version 1 | |
| http://hal.archives-ouvertes.fr/hal-00643521 | |
| oai:hal.archives-ouvertes.fr:hal-00643521 | |
| Contributeur : Brigitte Carles | |
| Soumis le : Mardi 22 Novembre 2011, 10:45:05 | |
| Dernière modification le : Mardi 22 Novembre 2011, 11:16:41 | |
