Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women

Mia Birkhøj Kjærstad (1) , Flemming Nielsen (1, 2) , Lene Nøhr-Jensen (2) , Stine Zwisler (2) , Kim Brøsen (2) , Helle Raun Andersen (1)

1 Department of Environmental Medicine, Institute of Public Health
2 Clinical Pharmacology, Institute of Public Health

Mots clés: Miconazole; Antifungal; CYP1A2; CYP3A4; Vaginal uptake

Mia Birkhøj Kjærstad, Flemming Nielsen, Lene Nøhr-Jensen, Stine Zwisler, Kim Brøsen, et al.. Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women. European Journal of Clinical Pharmacology, 2010, 66 (12), pp.1189-1197. ⟨10.1007/s00228-010-0906-2⟩. ⟨hal-00629462⟩