Facile functionalization of a fully fluorescent perfluorophenyl BODIPY: photostable thiol and amine conjugates

Guillaume Vives (1) , Carlo Giansante (1) , Robin Bofinger (1) , Guillaume Raffy (1) , André del Guerzo (1) , Brice Kauffmann (2) , Pinar Batat (1, 3) , Gediminas Jonusauskas (3) , Nathan D. Mcclenaghan (1)

1 ISM - Institut des Sciences Moléculaires
2 IECB - Institut Européen de Chimie et Biologie
3 LOMA - Laboratoire Ondes et Matière d'Aquitaine

Selective nucleophilic substitution on a perfluorophenyl unit comprising a BODIPY fluorophore using an alkanethiol or a primary amine offers a quantitative fluorophore labelling strategy, while retaining high photostability and emission quantum yields approaching unity.

Domaines: Optique [physics.optics]

Guillaume Vives, Carlo Giansante, Robin Bofinger, Guillaume Raffy, André del Guerzo, et al.. Facile functionalization of a fully fluorescent perfluorophenyl BODIPY: photostable thiol and amine conjugates. Chemical Communications, 2011, 47 (37), pp.10425-10427. ⟨10.1039/c1cc13778f⟩. ⟨hal-00628217⟩