Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors

Erich Brendel (1) , Matthias Ludwig (1) , Chetan Lathia (2) , Caroline Robert (3) , Stanislas Ropert (4) , Jean-Charles Soria (3) , Jean-Pierre Armand (5)

1 Bayer HealthCare AG
2 Bayer Corporation
3 IGR - Institut Gustave Roussy
4 AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris]
5 Institut Claudius Regaud

Mots clés: Sorafenib; Dacarbazine; AIC; Pharmacokinetics; Phase I

Erich Brendel, Matthias Ludwig, Chetan Lathia, Caroline Robert, Stanislas Ropert, et al.. Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology, 2010, 68 (1), pp.53-61. ⟨10.1007/s00280-010-1423-9⟩. ⟨hal-00619930⟩