Detection of doxorubicin hydrochloride accumulation in the rat brain after morphine treatment by mass spectrometry

Iacopo Sardi (1) , Giancarlo Marca (2) , Maria Grazia Giovannini (2) , Sabrina Malvagia (3) , Renzo Guerrini (3) , Lorenzo Genitori (3) , Maura Massimino (4) , Maurizio Aricò (5)

1 Department of Onco-Hematology and Neuro-Surgery Units
2 Department of Pharmacology
3 Department of Neuroscience
4 Department of Pediatrics, IRCCS Foundation
5 Department of Onco-Hematology

Mots clés: Rodent model; Mass spectrometry; Blood-brain barrier; Doxorubicin; Morphine

Iacopo Sardi, Giancarlo Marca, Maria Grazia Giovannini, Sabrina Malvagia, Renzo Guerrini, et al.. Detection of doxorubicin hydrochloride accumulation in the rat brain after morphine treatment by mass spectrometry. Cancer Chemotherapy and Pharmacology, 2010, 67 (6), pp.1333-1340. ⟨10.1007/s00280-010-1429-3⟩. ⟨hal-00616903⟩