Effects of infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women

Rajaa A. Mirghani (1, 2) , Ishraga Elagib (3) , Gehad Elghazali (3) , Urban Hellgren (1, 4) , Lars L. Gustafsson (1)

1 Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet
2 Unit of Pharmacology, Faculty of Medicine
3 Department of Biochemistry and Department of Microbiology and Immunology
4 Division of Infectious Diseases, Department of Medicine Karolinska Institutet

Mots clés: Malaria; Quinine; Metabolites; Pharmacokinetics; Pregnancy

Rajaa A. Mirghani, Ishraga Elagib, Gehad Elghazali, Urban Hellgren, Lars L. Gustafsson. Effects of infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women. European Journal of Clinical Pharmacology, 2010, 66 (12), pp.1229-1234. ⟨10.1007/s00228-010-0877-3⟩. ⟨hal-00615116⟩