Proposal of a new limited sampling strategy to predict CYP3A activity using a partial AUC of midazolam

Stephanie Katzenmaier (1) , Christoph Markert (1) , Gerd Mikus (1)

1 Department of Clinical Pharmacology and Pharmacoepidemiology

Mots clés: Midazolam; Metabolic clearance; CYP3A; Partial AUC; Limited sampling strategy

Stephanie Katzenmaier, Christoph Markert, Gerd Mikus. Proposal of a new limited sampling strategy to predict CYP3A activity using a partial AUC of midazolam. European Journal of Clinical Pharmacology, 2010, 66 (11), pp.1137-1141. ⟨10.1007/s00228-010-0878-2⟩. ⟨hal-00613129⟩