Rimonabant-induced apoptosis in leukemia cell lines: activation of caspase-dependent and -independent pathways.
Résumé
Rimonabant (SR141716), a cannabinoid CB1 receptor antagonist known for anti-obesity activity, has more recently been shown to inhibit tumor cell growth. Here we demonstrated the anti-tumor potential of SR141716 in leukemia-derived cell lines and its low toxicity in normal cells (PBMC).
Origine : Fichiers produits par l'(les) auteur(s)
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