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Article Dans Une Revue Journal of the American Chemical Society Année : 2011

Base Pairing Enhances Fluorescence and Favors Cyclobutane Dimer Formation Induced upon Absorption of UVA Radiation by DNA

A. Bányász
P. Changenet-Barret
Thierry Douki

Résumé

The photochemical properties of the DNA duplex (dA)20 3 (dT)20 are compared with those of the parent single strands. It is shown that base pairing increases the probability of absorbing UVA photons, probably due to the formation of charge-transfer states. UVA excitation induces fluorescence peaking at 420 nm and decaying on the nanosecond time scale. The fluorescence quantum yield, the fluorescence lifetime, and the quantum yield for cyclobutane dimer formation increase upon base pairing. Such behavior contrasts with that of the UVC-induced processes.
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Dates et versions

hal-00591797 , version 1 (10-05-2011)

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Citer

A. Bányász, I. Vaya, P. Changenet-Barret, T. Gustavsson, Thierry Douki, et al.. Base Pairing Enhances Fluorescence and Favors Cyclobutane Dimer Formation Induced upon Absorption of UVA Radiation by DNA. Journal of the American Chemical Society, 2011, 133, pp.5163-5165. ⟨10.1021/ja110879m⟩. ⟨hal-00591797⟩
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