SIGNAL TRANSDUCTION IN THE HUMAN THYROCYTE AND ITS PERVERSION IN THYROID TUMORS

Pierre P. Roger , Wilma C.G. van Staveren , Katia Coulonval , Jacques E. Dumont , Carine Maenhaut

The study of normal signal transduction pathways regulating the proliferation and differentiation of a cell type allows to predict and to understand the perversions of these pathways which lead to tumorigenesis. In the case of the human thyroid cell, three cascades are mostly involved in tumorigenesis:

Mots clés: caveats; Signal transduction; thyroid carcinomas; TSH pathways; growth factor pathway; models; caveats.

Pierre P. Roger, Wilma C.G. van Staveren, Katia Coulonval, Jacques E. Dumont, Carine Maenhaut. SIGNAL TRANSDUCTION IN THE HUMAN THYROCYTE AND ITS PERVERSION IN THYROID TUMORS. Molecular and Cellular Endocrinology, 2010, 321 (1), pp.3. ⟨10.1016/j.mce.2009.11.015⟩. ⟨hal-00582107⟩