Endogenous production of nitric oxide synthase inhibitors

Shelagh Anthony (1) , James Leiper (1) , Patrick Vallance (1)

1 UCL - University College of London [London]

Numerous reports have indicated that the plasma concentration of endogenously produced inhibitors of nitric oxide synthase are elevated in human disease states. In this review we discuss recent advances in our understanding of the enzymes responsible for the synthesis of these inhibitors.

Mots clés: asymmetric methylarginine; dimethylarginine dimethylaminohydrolase; nitric oxide synthase; protein-arginine methyltransferase

Shelagh Anthony, James Leiper, Patrick Vallance. Endogenous production of nitric oxide synthase inhibitors. Vascular Medicine, 2005, 10 (1), pp.S3-S9. ⟨10.1177/1358836X0501000102⟩. ⟨hal-00571345⟩