Thermal Characterizations of Silver-containing Bioactive Glass-coated Sutures

Jonny J. Blaker (1) , Aldo R. Boccaccini (1) , Showan N. Nazhat (2)

1 Respiratory Epidemiology and Public Health
2 Division of Biomaterials and Tissue Engineering

This study utilized and compared a number of thermal analysis methods to characterize the thermal properties of commercial sutures with and without antimicrobial coatings of silver-doped bioactive glass (AgBG) interlocking particulates. The effect of a slurry dipping technique used to coat resorbable Vicryl® (polyglactin 910) and non-resorbable Mersilk® surgical sutures with AgBG was investigated using conventional differential scanning calorimetry (DSC), high speed calorimetry (or HYPERDSC™), and modulated temperature DSC (MTDSC). These methods were compared in terms of their ability to resolve the thermal transitions of the types of suture materials. Differential thermal analysis (DTA) and thermogravimetric analysis (TGA) were used to verify the thermal degradation temperatures of these materials and to quantify the AgBG coatings on the sutures.

Mots clés: suture; silk; bioactive glass; silver ion; antibacterial; MTDSC; HYPERDSCTM

Jonny J. Blaker, Aldo R. Boccaccini, Showan N. Nazhat. Thermal Characterizations of Silver-containing Bioactive Glass-coated Sutures. Journal of Biomaterials Applications, 2005, 20 (1), pp.81-98. ⟨10.1177/0885328205054264⟩. ⟨hal-00570762⟩