Exothermal Characteristics and Release of Residual Monomers from Fiber-reinforced Oligomer-modified Acrylic Bone Cement

Mervi A. Puska (1) , Lippo V.J. Lassila (1) , Allan J. Aho (1) , Antti Yli-Urpo (1) , Pekka K. Vallittu (1) , Ilkka Kangasniemi (2)

1 Department of Prosthetic Dentistry & Biomaterials Research
2 Vivoxid Ltd.

The aim of this study is to determine the peak temperature of polymerization, the setting time and the release of residual monomers of a modified acrylic bone cement. PalacosR, a commercial bone cement, is used as the main component. The cement is modified by adding short glass fibers and resorbable oligomer fillers, and an additional cross-linking monomer. The test specimens are classified according to the composition of the bone cement matrix (i.e., oligomer-filler, glass-fiber reinforcement, and/or cross-linking monomer). The exothermal characteristics during autopolymerization are analyzed using a transducer connected with a computer. The quantities of residual monomers were analyzed from different test groups using high performance liquid chromatography (HPLC). The Δ value for the oligomer filler and the glass-fiber-containing acrylic bone cement is lower than that for the unmodified bone cement (2.1±0.8 vs. 23.5±4.2°C). The addition of a cross-linking monomer, EGDMA, shortens the setting time of the autopolymerization of the unmodified bone cement (7.1±0.9min vs. 3.3 ±0.3min). The quantity of the residual monomers released is higher in the modified bone cement than that in the unmodified cement. The cement that contains glass fibers and oligomer fillers has a considerably lower exothermal peak, whereas the total quantity of residual monomers released is increased.

Mots clés: acrylic bone cement; exothermic characteristics; release of residual monomer

Mervi A. Puska, Lippo V.J. Lassila, Allan J. Aho, Antti Yli-Urpo, Pekka K. Vallittu, et al.. Exothermal Characteristics and Release of Residual Monomers from Fiber-reinforced Oligomer-modified Acrylic Bone Cement. Journal of Biomaterials Applications, 2005, 20 (1), pp.51-64. ⟨10.1177/0885328205048647⟩. ⟨hal-00570758⟩