Distribution of genovars and the new variant of in the Göteborg area, Sweden

T. Lagergård (1) , R. Hadad (2) , P. Tunbäck (3) , L. Lindholm (4) , G.-B. Löwhagen (3) , M. Unemo (2)

1 Department of Biomedicine, Microbiology and Immunology
2 Department of Laboratory Medicine, Clinical Microbiology
3 Department of Dermatology
4 Gotagene AB

The aims of this study were to assess the proportion of the new variant of (nvCT) and the distribution of genovars among -positive patients in the Göteborg area, Sweden. Consecutive urine samples positive for using BD ProbeTec ET (177 patients, 88 men and 89 women) were collected. An nvCT-specific real-time polymerase chain reaction (PCR) assay was used to investigate the nvCT prevalence. To identify the genovars, a 990-bp DNA segment from 105 specimens was sequenced. Seventeen percent (30/177) of all specimens contained nvCT. Nine different genovars were identified. About 50% were of genovar E, followed by F 16%, G 11%, K 8%, and D 5%, representing about 90% of the specimens in Göteborg. The occurrence of nvCT and the dominance of genovar E in Göteborg is similar to those in other areas of Sweden. To cover about 90% of the infections in Sweden, the serovars D, E, F, G, and K should be included in future vaccines based on the major outer membrane protein.

Mots clés: Life Sciences

T. Lagergård, R. Hadad, P. Tunbäck, L. Lindholm, G.-B. Löwhagen, et al.. Distribution of genovars and the new variant of in the Göteborg area, Sweden. European Journal of Clinical Microbiology and Infectious Diseases, 2010, 29 (5), pp.609-611. ⟨10.1007/s10096-010-0887-1⟩. ⟨hal-00570704⟩