SAPHO syndrome in an adult with ulcerative colitis responsive to intravenous pamidronate: a case report and review of the literature

Keith Siau (1) , Catherine J. Laversuch (1)

1 Department of Rheumatology

Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare group of sterile, inflammatory osteoarticular disorders classically associated with skin lesions. It is occasionally associated with enteropathic disease such as ulcerative colitis. We present a 39-year-old patient with chronic ulcerative colitis who developed enteropathic SAPHO and responded well to pamidronate. We discuss the clinicopathological features with particular attention to bone pathology, and perform a literature review of this fascinating syndrome.

Mots clés: SAPHO; Inflammatory bowel disease; CRMO; Ulcerative colitis

Keith Siau, Catherine J. Laversuch. SAPHO syndrome in an adult with ulcerative colitis responsive to intravenous pamidronate: a case report and review of the literature. Rheumatology International, 2009, 30 (8), pp.1085-1088. ⟨10.1007/s00296-009-1021-5⟩. ⟨hal-00568300⟩