Non-destructive investigation of fibronectin adsorption on titanium surfaces using PM-RAIRS: effect of surface hydroxylation

Stéphanie Boudesocque (1) , Olivier Dargaud (1, 2) , Lorenzo Stievano (3, 1) , Christophe Méthivier (1) , Jean-Francois Lambert (1) , T. Coradin (4) , Claire-Marie Pradier (1)

1 LRS - Laboratoire de Réactivité de Surface
2 SGR - Saint-Gobain Recherche
3 ICGM ICMMM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier
4 LCMCP (site Paris VI) - Laboratoire de Chimie de la Matière Condensée de Paris (site Paris VI)

Polarisation-modulation reflection-absorption infrared spectroscopy (PM-RAIRS) is a useful non-destructive technique to study semi-quantitatively the adsorption of proteins on metal surfaces. In this work, we employed PM-RAIRS to study the effect of the degree of hydroxylation of the surface of titanium metal sheets, obtained by specific acidic or basic treatments, on the adsorption of fibronectin, a model plasma adhesion protein. Our results seem to indicate that the degree of hydroxylation does not influence significantly the adhesion properties of fibronectin, which is one of the main steps in titanium osseointegration process.

Domaines: Matériaux

Stéphanie Boudesocque, Olivier Dargaud, Lorenzo Stievano, Christophe Méthivier, Jean-Francois Lambert, et al.. Non-destructive investigation of fibronectin adsorption on titanium surfaces using PM-RAIRS: effect of surface hydroxylation. Surface and Interface Analysis, 2010, 42 (6-7), pp.466-470. ⟨10.1002/sia.3295⟩. ⟨hal-00558207⟩