Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients

C. Ausch , V. Buxhofer-Ausch , U. Olszewski , W. Hinterberger , E. Ogris , R. Schiessel , G. Hamilton

Soluble cytokeratin 18 (CK18; M65) and a caspase-cleaved fragment of CK18 (M30) have been used as biomarkers, corresponding to tumor cell death and apoptosis respectively.

Mots clés: colon cancer; cytokeratin 18; apoptosis; caspase; chemotherapy

C. Ausch, V. Buxhofer-Ausch, U. Olszewski, W. Hinterberger, E. Ogris, et al.. Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients. EJSO - European Journal of Surgical Oncology, 2009, 35 (11), pp.1164. ⟨10.1016/j.ejso.2009.02.007⟩. ⟨hal-00556281⟩