Positron Emission Tomography for monitoring response to neo-adjuvant therapy in patients with oesophageal and gastro-oesophageal junction carcinoma

S.A. Suttie (1) , A.E. Welch (2) , K.G.M. Park (3)

1 Department of Surgery and Molecular Oncology
2 Department of Biomedical Physics
3 Department of Surgery

The aim of this review is to consolidate our knowledge on an important and rapidly expanding area of expertise. Numerous methods for predicting response (in terms of pathological response and survival) to neo-adjuvant therapy (chemotherapy/chemoradiotherapy) in oesophageal and junctional cancers have been proposed. This review concerns itself only with the use of Positron Emission Tomography for such a purpose. At present there are no standardised criteria amongst PET trials as to what determines a response according to PET; what is the optimal time to perform PET in relation to the timing of neo-adjuvant therapy; what is the ideal method of quantifying PET tracer uptake.

Mots clés: Positron Emission Tomography; Oesophageal Cancer; Response; Chemotherapy

S.A. Suttie, A.E. Welch, K.G.M. Park. Positron Emission Tomography for monitoring response to neo-adjuvant therapy in patients with oesophageal and gastro-oesophageal junction carcinoma. EJSO - European Journal of Surgical Oncology, 2009, 35 (10), pp.1019. ⟨10.1016/j.ejso.2009.01.012⟩. ⟨hal-00556274⟩