How much could a microbicide's STI-efficacy contribute to reducing HIV-risk and the level of condom use needed to lower risk? Model estimates

Anna Mary Foss (1) , Peter Thomas Vickerman (1) , Michel Alary (2) , Charlotte Helen Watts (1)

1 LSHTM - London School of Hygiene and Tropical Medicine
2 Centre Hospitalier Affilié Universitaire de Québec

This study explores the potential contribution of a microbicide's STI-efficacy in reducing a female sex worker's (FSW's) risk of STI and HIV infection. The study then investigates whether the threshold, for the reduction in condom use following microbicide introduction that can be tolerated without increasing HIV-risk, is affected by the STI-efficacy.

Mots clés: HIV; condoms; mathematical models; sexually transmitted infections; vaginal microbicides

Anna Mary Foss, Peter Thomas Vickerman, Michel Alary, Charlotte Helen Watts. How much could a microbicide's STI-efficacy contribute to reducing HIV-risk and the level of condom use needed to lower risk? Model estimates. Sexually Transmitted Infections, 2009, 85 (4), pp.276. ⟨10.1136/sti.2008.032458⟩. ⟨hal-00552793⟩