Finite element analysis of vulnerable atherosclerotic plaques: A comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease

Umar Sadat (1) , Zhi-Yong Li (1) , Victoria E Young (1) , Martin J Graves (1) , Jonathan R Boyle (1) , Elizabeth A Warburton (1) , Kevin Varty (1) , Eoin O'Brien (1) , Jonathan H Gillard (1)

1 Addenbrooke's Hospital

There is considerable evidence that patients with carotid artery stenosis treated immediately after the ischaemic cerebrovascular event have a better clinical outcome than those who get delayed treatment. Biomechanical assessment of carotid plaques using high resolution magnetic resonance imaging (MRI) can help examine the relationship between the timing of carotid plaque symptomology and maximum simulated plaque stress concentration.

Mots clés: CEREBROVASCULAR DISEASE; MRI; NEUROSURGERY; STROKE; VASCULAR SURGERY

Umar Sadat, Zhi-Yong Li, Victoria E Young, Martin J Graves, Jonathan R Boyle, et al.. Finite element analysis of vulnerable atherosclerotic plaques: A comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease. Journal of Neurology, Neurosurgery and Psychiatry, 2010, 81 (3), pp.286. ⟨10.1136/jnnp.2009.190363⟩. ⟨hal-00552792⟩