Phase I dose-escalation study of brostallicin, a minor groove binder, in combination with cisplatin in patients with advanced solid tumors

F. Caponigro (1) , D. Lorusso (2) , G. Fornari (3) , C. Barone (2) , M. Merlano (4) , M. Airoldi (5) , M. Schena (6) , R. Macarthur (7) , S. Weitman (8) , M. G. Jannuzzo (9) , S. Crippa (9) , F. Fiorentini (10) , A. Petroccione (9) , S. Comis (9)

1 National Tumor Institute
2 Unicatt - Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma]
3 Valdese Hospital
4 S. Croce e Carle Hospital
5 S. Giovanni Antica Sede Hospital
6 S. Giovanni Battista Hospital
7 Columbia University Research Pharmacy
8 MCS
9 Nerviano Medical Sciences
10 Accelera

Mots clés: Brostallicin; Cisplatin; Phase I; Solid tumors

F. Caponigro, D. Lorusso, G. Fornari, C. Barone, M. Merlano, et al.. Phase I dose-escalation study of brostallicin, a minor groove binder, in combination with cisplatin in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology, 2009, 66 (2), pp.389-394. ⟨10.1007/s00280-009-1175-6⟩. ⟨hal-00552478⟩