On the interactions between Fusarium toxin-contaminated wheat and non-starch-polysaccharide hydrolyzing enzymes in diets of turkeys on performance, health and carry over of deoxynivalenol and zearalenone

Sven Dänicke (1)

1 Inst. of Animal Nutrition

1. Diets with increasing proportions of Fusarium toxin-contaminated wheat (0, 170, 340 and 510 g CW/kg) were fed to male turkeys (BUT big 6) from Day 21 to Day 56 of age. Each diet was tested with or without a non-starch-polysaccharide (NSP) hydrolyzing enzyme preparation. Dietary deoxynivalenol (DON) and zearalenone (ZON) concentrations were successively increased up to approximately 5.4 and 0.04 mg/kg, respectively. 2. Weight gain decreased slightly with increasing proportions of CW by 1.6, 0.7 and 3.6 % (plinear=0.044), whereas other performance parameters remained unaffected. NSP enzyme supplements to the diets had no influence. 3. The weight of the emptied jejunum plus ileum, relative to live weight, decreased in a dose-related fashion whereby the NSP enzyme exerted an additional weight-decreasing effect. A similar weight-decreasing NSP enzyme effect was noted for heart weights. Activity of glutamate-dehydrogenase in serum was significantly increased in groups fed the diets with the highest CW proportion, whereas ã-glutamyl-transferase remained unaltered. 4. Viscosity in the small intestine was significantly reduced by supplementing the diets with the NSP enzyme. This effect successively decreased with increasing proportions of the CW. 5. Concentrations of DON and of its de-epoxidized metabolite de-epoxy-DON in plasma, liver and breast meat were lower than the detection limits of 2 ng/mL (plasma) and 4 ng/g, respectively, of the applied HPLC-method. DON concentration in bile reached up to 13-23 ng/mL whereas de-epoxy-DON concentration was lower than 4 ng/mL. 6. ZON or its metabolites were not detectable in plasma, liver or breast meat (detection limits of the HPLC-method were 1 ng/g, 0.5 ng/g and 5 ng/g for ZON, á-zearalenol (ZOL) and â-ZOL, respectively). Concentrations of ZON and á-ZOL in bile increased with dietary ZON-concentration. The mean proportions of ZON, á-ZOL and â-ZOL of the sum of all three metabolites were 19, 77 and 4 %, respectively.

Mots clés: Life Sciences

Sven Dänicke. On the interactions between Fusarium toxin-contaminated wheat and non-starch-polysaccharide hydrolyzing enzymes in diets of turkeys on performance, health and carry over of deoxynivalenol and zearalenone. British Poultry Science, 2007, 48 (01), pp.39-48. ⟨10.1080/00071660601148161⟩. ⟨hal-00545308⟩