Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease

Hadi Molanaei (1, 2) , Juan Jesus Carrero (1) , Olof Heimbürger (1) , Louise Nordfors (3) , Bengt Lindholm (1) , Peter Stenvinkel (1) , Ingegerd Odar-Cederlöf (4) , Leif Bertilsson (4)

1 Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology
2 Division of Renal Medicine
3 Neurogenetics Unit, Department of Molecular Medicine and Surgery
4 Division of Clinical Pharmacology, Department of Laboratory Medicine of Karolinska Institutet

Mots clés: Codeine metabolism; CYP2D6 polymorphism; Hemodialysis

Hadi Molanaei, Juan Jesus Carrero, Olof Heimbürger, Louise Nordfors, Bengt Lindholm, et al.. Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease. European Journal of Clinical Pharmacology, 2009, 66 (3), pp.269-273. ⟨10.1007/s00228-009-0759-8⟩. ⟨hal-00540026⟩