Virulence of Classical Swine Fever Virus Isolates from Europe and other areas during 1996 until 2007

G. Floegel-Niesmann , S. Blome , H. Gerss-Dülmer , C. Bunzenthal , V. Moennig

Classical Swine Fever (CSF) has caused several outbreaks in EU Member States with grave economic consequences. Several times the diagnosis of CSF was made too late partially due to non-specific clinical signs which did not raise suspicion for CSF. Virulence of CSF virus isolates (CSFV) still remains a subject of discussion and speculation as sufficient knowledge is still not available. Six uncharacterised CSFV isolates from 1996 until 2007 were assessed in animal experiments for their clinical virulence in order to broaden the knowledge about circulating CSFV and thereby assist disease eradication. A clinical (CS) and pathological score were applied and further extended by additional parameters to a modified CS (mCS) including case fatality, antibody production and leukocyte count.

Mots clés: Classical Swine Fever; Virulence; Clinical score; Pathological lesions; Differential diagnosis; Case fatality

G. Floegel-Niesmann, S. Blome, H. Gerss-Dülmer, C. Bunzenthal, V. Moennig. Virulence of Classical Swine Fever Virus Isolates from Europe and other areas during 1996 until 2007. Veterinary Microbiology, 2009, 139 (1-2), pp.165. ⟨10.1016/j.vetmic.2009.05.008⟩. ⟨hal-00520662⟩