How to make a Teleost Adenohypophysis: Molecular Pathways of Pituitary development in Zebrafish

Hans-Martin Pogoda , Matthias Hammerschmidt

The anterior pituitary gland, or adenohypophysis, represents the key component of the vertebrate hypothalamo-hypophyseal axis, where it functions at the interphase of the nervous and endocrine system to regulate basic body functions like growth, metabolism and reproduction. For developmental biologists, the adenohypophysis serves as an excellent model system for the studies of organogenesis and differential cell fate specification. Previous research, mainly done in mouse, identified numerous extrinsic signaling cues and intrinsic transcription factors that orchestrate the gland's developmental progression.

Mots clés: Zebrafish; Adenohypophysis; Pituitary; Differential cell specification

Hans-Martin Pogoda, Matthias Hammerschmidt. How to make a Teleost Adenohypophysis: Molecular Pathways of Pituitary development in Zebrafish. Molecular and Cellular Endocrinology, 2009, 312 (1-2), pp.2. ⟨10.1016/j.mce.2009.03.012⟩. ⟨hal-00518308⟩