Personalized management of patients with inoperable alveolar echinococcosis undergoing treatment with albendazole: usefulness of positron-emission-tomography combined with serological and computed tomography follow-up.

J. Crouzet , F. Grenouillet (1) , E. Delabrousse (2) , O. Blagosklonov (3) , T. Thevenot , V. Di Martino (4) , R. Piarroux (1) , G. A. Mantion , S. Bresson-Hadni (1, 5)

1 LCE - Laboratoire Chrono-environnement (UMR 6249)
2 Applications des ultrasons à la thérapie
3 Service de Médecine nucléaire, biophysique, isotopes [CHRU Besançon]
4 API - Agents pathogènes et inflammation - UFC (EA 4266)
5 WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit

The present study aimed to identify a sub-group of inoperable alveolar echinococcosis (AE) patients undergoing long-term treatment with benzimidazole (BZM) who presented with an evolution suggestive of a parasitocidal effect. An evolution compatible with parasite death was observed in five patients.

Domaines: Hépatologie et Gastroentérologie

J. Crouzet, F. Grenouillet, E. Delabrousse, O. Blagosklonov, T. Thevenot, et al.. Personalized management of patients with inoperable alveolar echinococcosis undergoing treatment with albendazole: usefulness of positron-emission-tomography combined with serological and computed tomography follow-up.. Clinical Microbiology and Infection, 2010, 16 (6), pp.788-91. ⟨10.1111/j.1469-0691.2009.02924.x⟩. ⟨hal-00515720⟩