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| HAL : hal-00492056, version 1 |
| DOI : 10.1016/j.tetlet.2009.05.019 |
| Fiche détaillée |  Récupérer au format |
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| Tetrahedron Letters 50 (2009) 4251-4253 |
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| Synthesis of hexakis(2-keto-3,6-anhydro)cyclomaltohexaose: structural studies and Pb2+ complexation evaluation |
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| Thomas Berthelot 1Julia Chamot-Rooke 2 |
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| (2009) |
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| Molecules which scavenge heavy metals are of significant interest for medical applications such as toxic metal decontamination or medical imaging. We report the first synthesis of hexakis(2-keto-3,6-anhydro)cyclomaltohexaose in good yield using mild conditions (Swern oxidation). This potential synthon exhibits reactivity towards water which results in its total conversion into the per(gem-diol) derivative. The first computational study of Pb2+ complexation with per-3,6-anhydro-α-cyclodextrin in water is also reported. |
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| 1 : | Laboratoire des Solides Irradiés (LSI) |
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CNRS : UMR7642 – CEA : DSM/DRECAM – Polytechnique - X |
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| 2 : | Laboratoire des mécanismes réactionnels (DCMR) |
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CNRS : UMR7651 – Polytechnique - X |
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| Domaine | : | Chimie/Chimie de coordination Chimie/Chimie analytique |
| hal-00492056, version 1 | |
| http://hal.archives-ouvertes.fr/hal-00492056 | |
| oai:hal.archives-ouvertes.fr:hal-00492056 | |
| Contributeur : Gilles Frison | |
| Soumis le : Mardi 15 Juin 2010, 00:22:46 | |
| Dernière modification le : Mardi 15 Juin 2010, 00:22:46 | |
