A Study of the Protein Folding Dynamic
Résumé
In this paper, we propose two means to study the protein folding dynamic. We rely on the HP model to study the protein folding problem in a con- tinuous graphic environment. The amino acids evolve according to the boid rules, we observe a collective behavior due to the attraction between residues of H type. We propose a rst step to simulate a folding process. As well, we present a way to fold a protein when it is represented by an amino acid interaction network. This is a graph whose vertices are the pro- teins amino acids and whose edges are the interactions between them. We propose a genetic algorithm of reconstructing the graph of interactions between sec- ondary structure elements which describe the struc- tural motifs. The performance of our algorithms is validated experimentally.
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