EIN2, the central regulator of ethylene signalling, is localised at the ER membrane where it interacts with the ethylene receptor ETR1

Melanie Ma Bisson , Andrea Bleckmann , Silke Allekotte , Georg Groth (1)

1 Institute for Plant Biochemistry

Genetic studies have identified the membrane protein Ethylene Insensitive 2 (EIN2) as a central component of ethylene signalling in Arabidopsis. In addition, EIN2 might take part in multiple hormone signalling pathways and in responses to pathogens as demonstrated by recent genetic and biochemical studies. Here we show, by an integrated approach of in vivo and in vitro fluorescence techniques, that EIN2 is localised at the ER membrane where it shows specific interaction with the ethylene receptor protein ETR1.

Mots clés: Life Sciences

Melanie Ma Bisson, Andrea Bleckmann, Silke Allekotte, Georg Groth. EIN2, the central regulator of ethylene signalling, is localised at the ER membrane where it interacts with the ethylene receptor ETR1. Biochemical Journal, 2009, 424 (1), pp.1-6. ⟨10.1042/BJ20091102⟩. ⟨hal-00479232⟩