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| HAL : hal-00454542, version 1 |
| DOI : 10.1016/j.trac.2008.11.005 |
| CEMOA : http://cemadoc.cemagref.fr/cemoa/PUB00025810 |
| Fiche détaillée |  Récupérer au format |
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| Trends in Analytical Chemistry 28, 2 (2009) p. 237 - p. 244 |
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| Method validation for the analysis of estrogens (including conjugated compounds) in aqueous matrices |
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C. Miege 1P. Bados 1 |
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| Estrogens act as endocrine disruptors and are known to be discharged into the aquatic environment via effluents from wastewater- treatment plants (WWTPs). Efficient analytical protocols are needed to identify and to quantify estrogens in wastewaters and aquatic environments in order to study their sources, levels of exposure and modes of transfer. We developed and validated a new analytical method for estrogens in water. It quantifies five estrogenic hormones and their conjugated forms at the ng/L level in rivers, WWTP influents and effluents, with satisfactory precision (relative standard deviation of within-day analytical recoveries is usually <22%). The method is statistically specific, thanks to using perdeuterated hormones as internal surrogates, which proved to be an efficient means of correcting for matrix effects. |
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| 1 : | Qualité des eaux et prévention des pollutions (UR QELY) |
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CEMAGREF |
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| Domaine | : | Chimie/Chimie analytique Sciences du Vivant/Biochimie, Biologie Moléculaire/Biophysique Physique/Physique/Chimie-Physique Physique/Physique/Instrumentations et Détecteurs Sciences du Vivant/Toxicologie/Ecotoxicologie Sciences du Vivant/Biochimie, Biologie Moléculaire/Biologie moléculaire Sciences de l'Homme et Société/Etudes de l'environnement Sciences de l'environnement |
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| HORMONE – CHROMATOGRAPHIE – SPECTROMETRIE DE MASSE – VALIDATION – METHODE D'ANALYSE – OESTROGENE – CONJUGATED FORM – ENDOCRINE DISRUPTOR – ENVIRONMENTAL AQUEOUS MATRIX – ESTROGEN – LC-MS-MS – LIQUID CHROMATOGRAPHY – MASS SPECTROMETRY – MATRIX EFFECT – METHOD VALIDATION |
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| Liste des fichiers attachés à ce document : | |||||
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| hal-00454542, version 1 | |
| http://hal.archives-ouvertes.fr/hal-00454542 | |
| oai:hal.archives-ouvertes.fr:hal-00454542 | |
| Contributeur : Import Ws Irstea | |
| Déposé pour le compte de : | |
| Soumis le : Lundi 8 Février 2010, 17:08:14 | |
| Dernière modification le : Lundi 8 Février 2010, 17:23:54 | |
