Hubs identification in Amino Acids Interaction Networks

Omar Gaci (1) , Stefan Balev (1)

1 LITIS - Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes

In this paper we introduce the notion of protein interaction network. This is a graph whose vertices are the protein's amino acids and whose edges are the interactions between them. Using a graph theory approach, we identify a number of properties of these networks. We compare them to the general scale-free network model and we analyze the existence of nodes with a high interaction level.

Mots clés: amino acid; protein structure; interaction network; scale-free network; hub

Domaines: Bio-informatique [q-bio.QM]; Bio-Informatique, Biologie Systémique [q-bio.QM]

Omar Gaci, Stefan Balev. Hubs identification in Amino Acids Interaction Networks. The 7th ACS/IEEE International Conference on Computer Systems and Applications, May 2009, Rabat, Morocco. pp.96-102. ⟨hal-00431270⟩