Effects of Pharmacological versus Electrophysiological Treatments on Parkinsonian Dysprosody

François Viallet (1) , Bernard Teston (1) , Ludovic Jankowski (1) , Alain Purson (1) , Jean-Claude Peragut (2) , Jean Regis (2) , T. Wiitjas (2)

1 LPL - Laboratoire Parole et Langage
2 Service de neurochirurgie [CHU Marseille]

Dysprosody represents an essentiel part of speech intelligibility in Parkinson disease. To date the patients' management is based on two therapeutic interventions: the L-DOPA medication and/or the sub-thalamic stimulation. We study the speech production in two groups of ten patients (one group for each treatment), considering the prosodic parameters; pitch, intensity and duration.
The results of this study show a clear effect only on the pitch parameter (mean F0 and tonal extent) either with L-DOPA or with STN stimulation. No significant change are obtained with these treatments on intensity and duration.

Keywords: Parkinson; dysprosody; L-Dopa; sub-thalamic stimulation

Domains: Linguistics; Human health and pathology

François Viallet, Bernard Teston, Ludovic Jankowski, Alain Purson, Jean-Claude Peragut, et al.. Effects of Pharmacological versus Electrophysiological Treatments on Parkinsonian Dysprosody. Speech Prosody, Apr 2002, Aix-en-Provence, France. pp.679-682. ⟨hal-00250275⟩