 |
|
|
|
| HAL: hal-00150465, version 1 |
| PubMed: 17432936 |
| PubMed Central: 1851979 |
| DOI: 10.1371/journal.pgen.0030053 |
| Detailed view |  Export this paper |
|
|
| PLoS Genetics 3, 4 (2007) e53 |
|
|
|
|
| A tale of two oxidation states: bacterial colonization of arsenic-rich environments. |
|
|
| Daniel Muller 1, 2, 3Claudine Médigue 4, 5 |
|
|
| (2007-04-13) |
|
|
|
| Microbial biotransformations have a major impact on contamination by toxic elements, which threatens public health in developing and industrial countries. Finding a means of preserving natural environments-including ground and surface waters-from arsenic constitutes a major challenge facing modern society. Although this metalloid is ubiquitous on Earth, thus far no bacterium thriving in arsenic-contaminated environments has been fully characterized. In-depth exploration of the genome of the beta-proteobacterium Herminiimonas arsenicoxydans with regard to physiology, genetics, and proteomics, revealed that it possesses heretofore unsuspected mechanisms for coping with arsenic. Aside from multiple biochemical processes such as arsenic oxidation, reduction, and efflux, H. arsenicoxydans also exhibits positive chemotaxis and motility towards arsenic and metalloid scavenging by exopolysaccharides. These observations demonstrate the existence of a novel strategy to efficiently colonize arsenic-rich environments, which extends beyond oxidoreduction reactions. Such a microbial mechanism of detoxification, which is possibly exploitable for bioremediation applications of contaminated sites, may have played a crucial role in the occupation of ancient ecological niches on earth. |
|
|
|
|
|
|
|
|
|
|
|
| 1: | Génétique moléculaire, génomique, microbiologie (GMGM) |
|
|
|
CNRS : UMR7156 – Université Louis Pasteur - Strasbourg I |
|
|
| 2: | Institut d'Electronique du Solide et des Systèmes (InESS) |
|
|
|
CNRS : UMR7163 – Université Louis Pasteur - Strasbourg I |
|
|
| 3: | XLIM (XLIM) |
|
|
|
CNRS : UMR6172 – Université de Limoges |
|
|
| 4: | Structure et évolution des génomes (SEG) |
|
|
|
CNRS : UMR8030 – CNS – Université d'Evry-Val d'Essonne |
|
|
| 5: | Laboratoire de Biométrie et Biologie Evolutive (LBBE) |
|
|
|
Université Claude Bernard - Lyon I – CNRS : UMR5558 – INRIA |
|
|
| 6: | Biologie cellulaire et moléculaire des plantes et des bactéries (BCMPB) |
|
|
|
CNRS : UMR6191 – CEA : DSV/IBEB – Université de la Méditerranée - Aix-Marseille II |
|
|
| 7: | Laboratoire de microbiologie et génétique moléculaires (LMGM) |
|
|
|
CNRS : UMR5100 – Université Paul Sabatier - Toulouse III |
|
|
| 8: | Ecologie microbienne (EM) |
|
|
|
CNRS : UMR5557 – INRA : UR1193 – Université Claude Bernard - Lyon I – Ecole Nationale Vétérinaire de Lyon |
|
|
| 9: | Histoire et archéologie des mondes chrétiens et musulmans médiévaux (CIHAM) |
|
|
|
CNRS : UMR5648 – Université Lumière - Lyon II – Ecole des Hautes Etudes en Sciences Sociales (EHESS) – Ecole Normale Supérieure Lettres et Sciences Humaines |
|
|
| 10: | Institut de biologie structurale et microbiologie (IBSM) |
|
|
|
CNRS : IFR88 – Université de la Méditerranée - Aix-Marseille II – Université de Provence - Aix-Marseille I – Université Paul Cézanne - Aix-Marseille III – INSERM : IFR88 |
|
|
| 11: | Centre de géochimie de la surface (CGS) |
|
|
|
CNRS : UMR7517 – INSU – Université Louis Pasteur - Strasbourg I |
|
|
| 12: | Substances naturelles/chimie moléculaire |
|
|
|
CNRS : UMR7509 – Université Louis Pasteur - Strasbourg I – Ecole européenne de chimie polymères et matériaux de Strasbourg |
|
|
| 13: | Institut Pluridisciplinaire Hubert Curien (IPHC) |
|
|
|
CNRS : UMR7178 – Université Louis Pasteur - Strasbourg I |
|
|
|
|
|
|
|
|
|
| Subject | : | Life Sciences/Microbiology and Parasitology |
| hal-00150465, version 1 | |
| http://hal.archives-ouvertes.fr/hal-00150465 | |
| oai:hal.archives-ouvertes.fr:hal-00150465 | |
| From: Gilberte Niedergang | |
| Submitted on: Wednesday, 30 May 2007 15:45:36 | |
| Updated on: Tuesday, 26 February 2008 13:22:23 | |
