Chiral ferrocenyl diphosphines for asymmetric transfer hydrogenation of acetophenone

Jérôme Cabou (1) , Jacques S. Brocard (1) , Lydie Pélinski (1)

1 UCCS - Unité de Catalyse et Chimie du Solide - UMR 8181

The synthesis of new optically pure ferrocenyl diphosphines have been realized from (R)-(+)-N,N-dimethylaminoethylferrocene. Particularly, dissymmetric ferrocenyl diphosphines have been synthesized. The diphosphines have been used as ligands in asymmetric transfer hydrogenation of acetophenone in the presence of Ru catalysts.

Mots clés: Ferrocene; diphosphines; asymmetric transfer hydrogenation

Domaines: Chimie organique; Catalyse

Jérôme Cabou, Jacques S. Brocard, Lydie Pélinski. Chiral ferrocenyl diphosphines for asymmetric transfer hydrogenation of acetophenone. Tetrahedron Letters, 2005, 46, pp.1185-1188. ⟨10.1016/j.tetlet.2004.12.059⟩. ⟨hal-00115517⟩