Enhanced regioselectivity in palladium-catalysed asymmetric methoxycarbonylation of styrene using phosphetanes as chiral ligands

Bianca Munoz (1, 2) , Angela Marinetti (3) , Aurora Ruiz (2) , Sergio Castillon (1) , Carmen Claver (2)

1 Departament de Quimica Organica
2 Departament de Química Física i Inorgànica
3 ICSN - Institut de Chimie des Substances Naturelles

The palladium-catalysed asymmetric methoxycarbonylation of styrene has been investigated for the first time using phosphetanes as chiral ligands and showed good catalytic activity, excellent regioselectivity to the branched product and enantioselectivity up to 29%.

Mots clés: Palladium; Methoxycarbonylation; Asymmetric; Phosphetanes; Styrene

Domaines: Chimie organique

Bianca Munoz, Angela Marinetti, Aurora Ruiz, Sergio Castillon, Carmen Claver. Enhanced regioselectivity in palladium-catalysed asymmetric methoxycarbonylation of styrene using phosphetanes as chiral ligands. Inorganic Chemistry Communications, 2005, 8 (12), pp.1113-1115. ⟨10.1016/j.inoche.2005.09.006⟩. ⟨hal-00114840v2⟩